The BRADLEY DEPARTMENT of ELECTRICAL and COMPUTER ENGINEERING

Jason Jianhua Xuan | ECE | Virginia Tech

ECE PROFILE

Jason Jianhua Xuan

Picture of Jason Jianhua Xuan

Office:
Virginia Tech Research Center - Arlington

Mailing Address:
Virginia Tech Research Center - Arlington
Room 4-030900 N. Glebe Road
Arlington, VA 22203

(571) 858-3151
(571) 858-3015
xuan@vt.edu


Education:

Ph.D., Electrical Engineering, University of Maryland, USA, 1997
Ph.D., Electrical Engineering, Zhejiang University, China, 1991
M.S., Electrical Engineering, Zhejiang University, China, 1988
B.S., Electrical Engineering, Zhejiang University, China, 1985

Teaching Interests:

Deep learning, digital image processing, multimedia signal processing, computer vision, statistical learning for bioinformatics, computational systems biology, machine learning, information visualization, computer graphics, pattern recognition, and information retrieval.

Research Interests:

Deep genomics, computational systems biology, bioinformatics for cancer research, advanced medical image analysis, and image guided radiation therapy.

Grants and Projects:
  • Uncovering Estrogen Receptor-Signaling Networks to Overcome Endocrine Resistance (NIH/NCI R01CA149653; PI)
  • Transgenerational Effects of Maternal High Fat Diet During Pregnancy of Breast Cancer (NIH/NCI R01CA164384; Co-PI)
  • Collaborative research in integrative cancer biology (NIH/NCI U01CA184902; Co-I)
Selected Publications:
  • Title: ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic model of ChIP-seq profiles
    Author(s): X. Chen, J.-G. Jung, A. N. Shajahan-Haq, R. Clarke, I.-M. Shih, Y. Wang, L. Magnani, T.-L. Wang, and J. Xuan*
    Journal: Nucleic Acids Res. (Impact Factor (IF) = 9.112), 44(7):e65, 2016
  • Title: Identifying protein interaction subnetworks by a bagging Markov random field-based method
    Author(s): L. Chen, J. Xuan*, R. B. Riggins, Y. Wang and R. Clarke
    Journal: Nucleic Acids Res. (IF = 8.808), 41(2):e42, 2013
  • Title: DM-BLD: Differential methylation detection using a hierarchical Bayesian model exploiting local dependency
    Author(s): X. Wang, J. Gu, L. Hilakivi-Clarke, R. Clarke, and J. Xuan*
    Journal: Bioinformatics (IF = 7.307; 2016 ISI), 33(2):161-168, 2017
  • Title: PSSV: A novel pattern-based probabilistic approach for somatic structural variation identification
    Author(s): X. Chen, X. Shi, L. Hilakivi-Clarke, A. N. Shajahan-Haq, R. Clarke, and J. Xuan*
    Journal: Bioinformatics (IF = 7.307; 2016 ISI), 33(2):177-183, 2017
  • Title: BMRF-Net: a software tool for identification of protein interaction subnetworks by a bagging Markov random field-based method
    Author(s): X. Shi, R. O. Barnes, L. Chen, A. N. Shajahan-Haq, L. Hilakivi-Clarke, R. Clarke, Y. Wang, J. Xuan*
    Journal: Bioinformatics (IF=5.766), 31(14):2412-2414, 2015
  • Title: BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency
    Author(s): X. Shi, X. Wang, A. Shajahan, L. Hilakivi-Clarke, R. Clarke and J. Xuan*
    Journal: BMC Genomics (IF=3.867), 16(Suppl 7):S10, 2015
  • Title: Robust identification of transcriptional regulatory networks using a Gibbs sampler on outlier sum statistic
    Author(s): J. Gu, J. Xuan*, R. B. Riggins, L. Chen, Y. Wang, and R. Clarke
    Journal: Bioinformatics (IF=5.323), 28(15):1990-1997, 2012
  • Title: Definition of NOTCH3 target genes in ovarian cancer
    Author(s): X. Chen, M. M. Thiaville, L. Chen, A. Stoeck, J. Xuan*, M. Gao, I.-M. Shih, and T.-L. Wang
    Journal: Cancer Research (IF = 8.650), 72(9):2294-2303, 2012
  • Title: Identifying cancer biomarkers by network-constrained support vector machines
    Author(s): L. Chen, J. Xuan*, R. B. Riggins, R. Clarke, and Y. Wang
    Journal: BMC Systems Biology (IF = 3.15), 5:161, 2011
  • Title: Multilevel support vector regression analysis to identify condition-specific regulatory networks
    Author(s): L. Chen, J. Xuan*, R. B. Riggins, Y. Wang, E. P. Hoffman, and R. Clarke
    Journal: Bioinformatics (IF = 4.877), 26(11):1416-1422, 2010